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MUTYH Rabbit pAb

Anti-MUTYH Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216665

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216665
Product Name:   Anti-MUTYH Rabbit Polyclonal Antibody
Synonyms:   MYH
UNIPROT ID:   Q9UIF7 (Gene Accession – BC003178 )
Background:    This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Fusion protein of human MUTYH
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 25-100;WB: 1000-5000;ELISA: 2000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 216665(MUTYH Antibody) at a dilution of 1/25(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the fusion protein and then with 216665(Anti-MUTYH Antibody) at dilution 1/25.

The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 216665(Anti-MUTYH Antibody) at a dilution of 1/25.

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with fusion protein and then with D221013(Anti-MUTYH Antibody) at dilution 1/25.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: Hela cells;
Primary antibody: 216665(MUTYH Antibody) at dilution 1/500;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 1 minute
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