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NOX4 Rabbit pAb

Anti-NOX4 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216686

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216686
Product Name:   Anti-NOX4 Rabbit Polyclonal Antibody
Synonyms:   KOX; KOX-1; RENOX
UNIPROT ID:   Q9NPH5 (Gene Accession – BC040105 )
Background:    This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009]
Immunogen:    Fusion protein of human NOX4
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Cell Biology, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 216686(NOX4 Antibody) at a dilution of 1/60(Cytoplasm and Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 216686(Anti-NOX4 Antibody) at dilution 1/60.
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