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PEBP1 Rabbit pAb

Anti-PEBP1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216738

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216738
Product Name:   Anti-PEBP1 Rabbit Polyclonal Antibody
Synonyms:   PBP; HCNP; PEBP; RKIP; HCNPpp; PEBP-1
UNIPROT ID:   P30086 (Gene Accession – BC031102 )
Background:    Phosphatidylethanolamine-binding protein 1 is a protein that in humans is encoded by the PEBP1 gene. Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase By similarity. Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation.
Immunogen:    Fusion protein of human PEBP1
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 500-2000;ELISA: 1000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Cancer, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 216738(PEBP1 Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the fusion protein and then with 216738(Anti-PEBP1 Antibody) at dilution 1/50.

The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 216738(Anti-PEBP1 Antibody) at a dilution of 1/50.

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with fusion protein and then with D221145(Anti-PEBP1 Antibody) at dilution 1/50.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-4: A549 cells, K562 cells, hela cells, hepG2 cells;
Primary antibody: 216738(PEBP1 Antibody) at dilution 1/475;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 40 seconds
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