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PRMT2 Rabbit pAb

Anti-PRMT2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216742

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216742
Product Name:   Anti-PRMT2 Rabbit Polyclonal Antibody
Synonyms:   HRMT1L1
UNIPROT ID:   P55345 (Gene Accession – BC000727 )
Background:    Protein arginine N-methyltransferase 2 is an enzyme that in humans is encoded by the PRMT2 gene. Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. Acts as a coactivator (with NCOA2) of the androgen receptor (AR)-mediated transactivation. Acts as a coactivator (with estrogen) of estrogen receptor (ER)-mediated transactivation. Enhances PGR, PPARG, RARA-mediated transactivation. May inhibit NF-kappa-B transcription and promote apoptosis. Represses E2F1 transcriptional activity (in a RB1-dependent manner). May be involved in growth regulation.
Immunogen:    Fusion protein of human PRMT2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human gastric cancer tissue using 216742(PRMT2 Antibody) at a dilution of 1/20(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with the fusion protein and then with 216742(Anti-PRMT2 Antibody) at dilution 1/20.

The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using 216742(Anti-PRMT2 Antibody) at a dilution of 1/20.

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with fusion protein and then with D221152(Anti-PRMT2 Antibody) at dilution 1/20.
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