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RETNLB Rabbit pAb

Anti-RETNLB Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216763

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216763
Product Name:   Anti-RETNLB Rabbit Polyclonal Antibody
Synonyms:   XCP2; FIZZ1; FIZZ2; HXCP2; RELMb; RELMbeta; RELM-beta
UNIPROT ID:   Q9BQ08 (Gene Accession – BC113502 )
Background:    Resistin-like beta is a protein that in humans is encoded by the RETNLB gene. An infusion of either resistin or RELMB in rats rapidly induced severe hepatic but not peripheral insulin resistance. Increases in circulating resistin or RELMB levels markedly stimulated hepatic glucose production despite the presence of fixed physiologic insulin levels. This enhanced rate of glucose output was due to increased flux through glucose-6-phosphatase. The results supported the notion that a novel family of fat- and gut-derived circulating proteins modulates hepatic insulin action.
Immunogen:    Fusion protein of human RETNLB
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 216763(RETNLB Antibody) at a dilution of 1/20(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 216763(Anti-RETNLB Antibody) at dilution 1/20.

The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using 216763(Anti-RETNLB Antibody) at a dilution of 1/20.

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with fusion protein and then with D221195(Anti-RETNLB Antibody) at dilution 1/20.
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