Email: info@neweastbio.com   |  Call: 6109452007

SOD1 Rabbit pAb

Anti-SOD1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216794

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216794
Product Name:   Anti-SOD1 Rabbit Polyclonal Antibody
Synonyms:   ALS; SOD; ALS1; IPOA; STAHP; hSod1; HEL-S-44; homodimer
UNIPROT ID:   P00441 (Gene Accession – BC001034 )
Background:    The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. In addition, this protein contains an antimicrobial peptide that displays antibacterial, antifungal, and anti-MRSA activity against E. coli, E. faecalis, S. aureus, S. aureus MRSA LPV+, S. agalactiae, and yeast C. krusei. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.
Immunogen:    Fusion protein of human SOD1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cancer, Metabolism, Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 216794(SOD1 Antibody) at a dilution of 1/60(Cytoplasm and Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 216794(Anti-SOD1 Antibody) at dilution 1/60.
          Publications