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TIMP2 Rabbit pAb

Anti-TIMP2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216839

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216839
Product Name:   Anti-TIMP2 Rabbit Polyclonal Antibody
Synonyms:   CSC-21K
UNIPROT ID:   P16035 (Gene Accession – BC052605 )
Background:    This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.
Immunogen:    Fusion protein of human TIMP2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cardiovascular, Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 216839(TIMP2 Antibody) at a dilution of 1/20(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 216839(Anti-TIMP2 Antibody) at dilution 1/20.

The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 216839(Anti-TIMP2 Antibody) at a dilution of 1/20.

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with fusion protein and then with D221342(Anti-TIMP2 Antibody) at dilution 1/20.
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