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TRADD Rabbit pAb

Anti-TRADD Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216846

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216846
Product Name:   Anti-TRADD Rabbit Polyclonal Antibody
Synonyms:   Hs.89862
UNIPROT ID:   Q15628 (Gene Accession – BC004491 )
Background:    The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway.
Immunogen:    Fusion protein of human TRADD
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 100-300;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 216846(TRADD Antibody) at a dilution of 1/75(Nucleus and Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the fusion protein and then with 216846(Anti-TRADD Antibody) at dilution 1/75.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 216846(Anti-TRADD Antibody) at a dilution of 1/75.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with fusion protein and then with D221354(Anti-TRADD Antibody) at dilution 1/75.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: Mouse liver tissue, HUVEC cell lysates;
Primary antibody: 216846(TRADD Antibody) at dilution 1/500;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 30 seconds
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