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TERF1 Rabbit pAb

Anti-TERF1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216857

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216857
Product Name:   Anti-TERF1 Rabbit Polyclonal Antibody
Synonyms:   TRF; PIN2; TRF1; TRBF1; t-TRF1; hTRF1-AS
UNIPROT ID:   P54274 (Gene Accession – BC029378 )
Background:    This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products.
Immunogen:    Fusion protein of human TERF1
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 25-100;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 216857(TERF1 Antibody) at a dilution of 1/30(Cytoplasm and Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the fusion protein and then with 216857(Anti-TERF1 Antibody) at dilution 1/30.

The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using 216857(Anti-TERF1 Antibody) at a dilution of 1/30.

In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with fusion protein and then with D221366(Anti-TERF1 Antibody) at dilution 1/30.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: A549 cell lysate;
Primary antibody: 216857(TERF1 Antibody) at dilution 1/400;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 10 seconds
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