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ABI2 Rabbit pAb

Anti-ABI2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216903

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216903
Product Name:   Anti-ABI2 Rabbit Polyclonal Antibody
Synonyms:   AIP1; ABI-2; ABI2B; AIP-1; AblBP3; argBP1; SSH3BP2; argBPIA; argBPIB
UNIPROT ID:   Q9NYB9 (Gene Accession – BC001439 )
Background:    May act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA. As component of the WAVE1 comple,x required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes.
Immunogen:    Fusion protein of human ABI2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 216903(ABI2 Antibody) at a dilution of 1/45(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the fusion protein and then with 216903(Anti-ABI2 Antibody) at dilution 1/45.
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