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CNN3 Rabbit pAb

Anti-CNN3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216912

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216912
Product Name:   Anti-CNN3 Rabbit Polyclonal Antibody
Synonyms:   
UNIPROT ID:   Q15417 (Gene Accession – BC025372 )
Background:    This gene encodes a protein with a markedly acidic C terminus; the basic N-terminus is highly homologous to the N-terminus of a related gene, CNN1. Members of the CNN gene family all contain similar tandemly repeated motifs. This encoded protein is associated with the cytoskeleton but is not involved in contraction. Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
Immunogen:    Fusion protein of human CNN3
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 25-100;WB: 500-2000;ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 216912(CNN3 Antibody) at a dilution of 1/15(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the fusion protein and then with 216912(Anti-CNN3 Antibody) at dilution 1/15.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 216912(Anti-CNN3 Antibody) at a dilution of 1/15.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with fusion protein and then with D221465(Anti-CNN3 Antibody) at dilution 1/15.

Gel: 10%SDS-PAGE, Lysate: 40 μg;
Lane 1-3: Human fetal kidney tissue, 293T cells, human fetal lung tissue;
Primary antibody: 216912(CNN3 Antibody) at dilution 1/300;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 1 minute
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