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ATG5 Rabbit pAb

Anti-ATG5 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217018

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217018
Product Name:   Anti-ATG5 Rabbit Polyclonal Antibody
Synonyms:   ASP; APG5; APG5L; hAPG5; APG5-LIKE
UNIPROT ID:   Q9H1Y0 (Gene Accession – BC002699 )
Background:    Autophagy protein 5 is a protein that in humans is encoded by the ATG5 gene. It is an E3 ubiquitinligase which is necessary for autophagy due to its role in autophagosome elongation. It is activated by ATG7 and forms a complex with ATG12 and ATG16L1. This complex is necessary for LC3-1 conjugation to PE to form LC3-II.
Immunogen:    Fusion protein of human ATG5
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 1000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer, Cell Biology, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colon cancer tissue using 217018(ATG5 Antibody) at a dilution of 1/40(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with the fusion protein and then with 217018(Anti-ATG5 Antibody) at dilution 1/40.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 217018(Anti-ATG5 Antibody) at a dilution of 1/40.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with fusion protein and then with D221650(Anti-ATG5 Antibody) at dilution 1/40.
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