Email: info@neweastbio.com   |  Call: 6109452007

USP2 Rabbit pAb

Anti-USP2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217083

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217083
Product Name:   Anti-USP2 Rabbit Polyclonal Antibody
Synonyms:   USP9; UBP41
UNIPROT ID:   O75604 (Gene Accession – BC002854 )
Background:    This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Immunogen:    Fusion protein of human USP2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 217083(USP2 Antibody) at a dilution of 1/30(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 217083(Anti-USP2 Antibody) at dilution 1/30.

The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 217083(Anti-USP2 Antibody) at a dilution of 1/30.

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with fusion protein and then with D221761(Anti-USP2 Antibody) at dilution 1/30.
          Publications