Email: info@neweastbio.com   |  Call: 6109452007

DNM1L Rabbit pAb

Anti-DNM1L Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217369

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217369
Product Name:   Anti-DNM1L Rabbit Polyclonal Antibody
Synonyms:   DLP1; DRP1; DVLP; EMPF; OPA5; EMPF1; DYMPLE; HDYNIV
UNIPROT ID:   O00429 (Gene Accession – BC024590 )
Background:    This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer’s disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]
Immunogen:    Fusion protein of human DNM1L
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 200-300;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Cancer, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 217369(DNM1L Antibody) at a dilution of 1/160(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 217369(Anti-DNM1L Antibody) at dilution 1/160.

The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 217369(Anti-DNM1L Antibody) at a dilution of 1/160.

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with fusion protein and then with D222247(Anti-DNM1L Antibody) at dilution 1/160.

Gel: 6%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: Raji cell and Mouse brain tissue lysates;
Primary antibody: 217369(DNM1L Antibody) at dilution 1/800;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 1 minute
          Publications