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GADD45B Rabbit pAb

Anti-GADD45B Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217463

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217463
Product Name:   Anti-GADD45B Rabbit Polyclonal Antibody
Synonyms:   MYD118; GADD45BETA
UNIPROT ID:   O75293 (Gene Accession – BC113466 )
Background:    This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth.
Immunogen:    Fusion protein of human GADD45B
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Epigenetics and Nuclear Signaling, Cancer, Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human thyroid cancer tissue using 217463(GADD45B Antibody) at a dilution of 1/40(Cytoplasm).

Immunohistochemistry analysis of paraffin-embedded Human brain tissue using 217463(Anti-GADD45B Antibody) at a dilution of 1/40.
          Publications