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INSIG2 Rabbit pAb

Anti-INSIG2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217543

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217543
Product Name:   Anti-INSIG2 Rabbit Polyclonal Antibody
Synonyms:   
UNIPROT ID:   Q9Y5U4 (Gene Accession – BC022475 )
Background:    The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.
Immunogen:    Fusion protein of human INSIG2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Metabolism, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 217543(INSIG2 Antibody) at a dilution of 1/30(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 217543(Anti-INSIG2 Antibody) at dilution 1/30.
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