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PIN1 Rabbit pAb

Anti-PIN1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217694

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217694
Product Name:   Anti-PIN1 Rabbit Polyclonal Antibody
Synonyms:   DOD; UBL5
UNIPROT ID:   Q13526 (Gene Accession – BC002899 )
Background:    Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival.
Immunogen:    Fusion protein of human PIN1
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 25-100;WB: 200-1000;ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 217694(PIN1 Antibody) at a dilution of 1/25(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 217694(Anti-PIN1 Antibody) at dilution 1/25.

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 217694(Anti-PIN1 Antibody) at a dilution of 1/25.

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with fusion protein and then with D222878(Anti-PIN1 Antibody) at dilution 1/25.

Gel: 12%SDS-PAGE, Lysate: 40 μg;
Lane: Mouse brain tissue;
Primary antibody: 217694(PIN1 Antibody) at dilution 1/300;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 1 minute
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