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RASGEF1A Rabbit pAb

Anti-RASGEF1A Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217740

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217740
Product Name:   Anti-RASGEF1A Rabbit Polyclonal Antibody
Synonyms:   CG4853
UNIPROT ID:   Q8N9B8 (Gene Accession – BC022548 )
Background:    RASGEF1A (RasGEF domain family, member 1A) is a 481 amino acid guanine-nucleotide exchange factor (GEF) for H-Ras, K-Ras, and N-Ras. RASGEF1A may also play a role in cell migration. RASFEG1A is highly expressed in spinal chord and brain and contains one N-terminal Ras-GEF domain and one Ras-GEF domain. The gene that encodes RASGEF1A maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome.
Immunogen:    Fusion protein of human RASGEF1A
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: Oct-50; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human brain tissue using 217740(RASGEF1A Antibody) at a dilution of 1/20(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with the fusion protein and then with 217740(Anti-RASGEF1A Antibody) at dilution 1/20.
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