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SMARCB1 Rabbit pAb

Anti-SMARCB1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217840

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217840
Product Name:   Anti-SMARCB1 Rabbit Polyclonal Antibody
Synonyms:   RDT; INI1; SNF5; Snr1; BAF47; MRD15; RTPS1; Sfh1p; hSNFS; SNF5L1; SWNTS1; PPP1R144
UNIPROT ID:   Q12824 (Gene Accession – BC117114 )
Background:    The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Fusion protein of human SMARCB1
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 30-150;WB: 200-1000;ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 217840(SMARCB1 Antibody) at a dilution of 1/35(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 217840(Anti-SMARCB1 Antibody) at dilution 1/35.

The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 217840(Anti-SMARCB1 Antibody) at a dilution of 1/35.

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with fusion protein and then with D223195(Anti-SMARCB1 Antibody) at dilution 1/35.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-3: Jurkat cells, K562 cells, hepg2 cells;
Primary antibody: 217840(SMARCB1 Antibody) at dilution 1/450;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 10 seconds
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