Email: info@neweastbio.com   |  Call: 6109452007

KEAP1 Rabbit pAb

Anti-KEAP1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217950

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217950
Product Name:   Anti-KEAP1 Rabbit Polyclonal Antibody
Synonyms:   INrf2; KLHL19
UNIPROT ID:   Q14145 (Gene Accession – BC002417 )
Background:    This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
Immunogen:    Fusion protein of human KEAP1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 217950(KEAP1 Antibody) at a dilution of 1/70(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 217950(Anti-KEAP1 Antibody) at dilution 1/70.
          Publications