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MIOX Rabbit pAb

Anti-MIOX Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218145

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218145
Product Name:   Anti-MIOX Rabbit Polyclonal Antibody
Synonyms:   ALDRL6
UNIPROT ID:   Q9UGB7 (Gene Accession – BC012025 )
Background:    Myo-inositol oxygenase (MIOX), also known as ALDRL6, is a renal-specific member of the Aldo-keto reductase family. It catalyzes the first committed step in the Myo-inositol metabolism pathway and is widely distributed in mammalian tissues. Human Myo-inositol oxygenase shares 91% and 96% sequence homology with mouse and pig Myo-inositol oxygenase homologs, respectively. Myo-inositol oxygenase is responsible for the oxidative cleavage of Myo-inositol (MI) and its epimer D-chiro inositol (DCI) to D-glucuronate. The dioxygen-dependent cleavage of the C1-C6 bond in Myo-inositol is accomplished through the utilization of the Fe(II)/Fe(III) binuclear iron center of MIOX. Myo-inositol oxygenase has also been implicated in complications of diabetes, including diabetic nephropathy.
Immunogen:    Full length fusion protein
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 20-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human brain tissue using 218145(MIOX Antibody) at a dilution of 1/25(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with the fusion protein and then with 218145(Anti-MIOX Antibody) at dilution 1/25.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 218145(Anti-MIOX Antibody) at a dilution of 1/25.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with fusion protein and then with D223814(Anti-MIOX Antibody) at dilution 1/25.
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