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YPEL3 Rabbit pAb

Anti-YPEL3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218271

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218271
Product Name:   Anti-YPEL3 Rabbit Polyclonal Antibody
Synonyms:   
UNIPROT ID:   P61236 (Gene Accession – BC005009 )
Background:    YPEL3 (yippee-like 3) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL3 is a p53-regulated gene whose expression is induced by DNA damage and in turn induces cellular senescence. It appears to function as a tumor suppressor as it is downregulated in colon and breast tumors. Involved in proliferation and apoptosis in myeloid precursor cells.
Immunogen:    Full length fusion protein
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 20-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 218271(YPEL3 Antibody) at a dilution of 1/30(Nucleus ).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 218271(Anti-YPEL3 Antibody) at dilution 1/30.
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