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UBE4A Rabbit pAb

Anti-UBE4A Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218317

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218317
Product Name:   Anti-UBE4A Rabbit Polyclonal Antibody
Synonyms:   E4; UFD2; UBOX2
UNIPROT ID:   Q14139 (Gene Accession – BC112367 )
Background:    This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn’s disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Immunogen:    Fusion protein of human UBE4A
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 218317(UBE4A Antibody) at a dilution of 1/30(Cytoplasm and Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the fusion protein and then with 218317(Anti-UBE4A Antibody) at dilution 1/30.

The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 218317(Anti-UBE4A Antibody) at a dilution of 1/30.

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with fusion protein and then with D224148(Anti-UBE4A Antibody) at dilution 1/30.
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