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MCPH1 Rabbit pAb

Anti-MCPH1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218373

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218373
Product Name:   Anti-MCPH1 Rabbit Polyclonal Antibody
Synonyms:   MCT; BRIT1
UNIPROT ID:   Q8NEM0 (Gene Accession – BC030702 )
Background:    This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described.
Immunogen:    Fusion protein of human MCPH1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-300; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human gastric cancer tissue using 218373(MCPH1 Antibody) at a dilution of 1/110(Nucleus and Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with the fusion protein and then with 218373(Anti-MCPH1 Antibody) at dilution 1/110.

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 218373(Anti-MCPH1 Antibody) at a dilution of 1/110.

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with fusion protein and then with D224277(Anti-MCPH1 Antibody) at dilution 1/110.
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