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BUD31 Rabbit pAb

Anti-BUD31 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218381

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218381
Product Name:   Anti-BUD31 Rabbit Polyclonal Antibody
Synonyms:   G10; EDG2; Cwc14; EDG-2; fSAP17; YCR063W
UNIPROT ID:   P41223 (Gene Accession – BC022821 )
Background:    BUD31 (Protein G10 homolog, EDG-2) is a 144 amino acid protein encoded by the human gene BUD31. BUD31 is a nuclear protein that belongs to the BUD31 (G10) family. BUD31 is found on chromosome 7 which is about 158 milllion bases long, encodes over 1,000 genes and makes up about 5% of the human genome. Chromosome 7 has been linked to osteogenesis imperfecta, Pendred syndrome, lissencephaly, citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the long (q) arm of human chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia.
Immunogen:    Full length fusion protein
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-300;WB: 1000-5000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 218381(BUD31 Antibody) at a dilution of 1/75(Cytoplasm or Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 218381(Anti-BUD31 Antibody) at dilution 1/75.

The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 218381(Anti-BUD31 Antibody) at a dilution of 1/75.

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with fusion protein and then with D224293(Anti-BUD31 Antibody) at dilution 1/75.

Gel: 12%SDS-PAGE, Lysate: 40 μg;
Lane 1-7: Human testis tissue, Mouse brain tissue, Mouse heart tissue, PC-3 cell, 231 cell, Raji and Jurkat cell lysates;
Primary antibody: 218381(BUD31 Antibody) at dilution 1/800;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 10 seconds
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