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C12orf10 Rabbit pAb

Anti-C12orf10 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218383

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218383
Product Name:   Anti-C12orf10 Rabbit Polyclonal Antibody
Synonyms:   MYG; MYG1; Gamm1; MST024; MSTP024
UNIPROT ID:   Q9HB07 (Gene Accession – BC028904 )
Background:    C12orf10, also known as MYG1, MYG1 is a 376 amino acid nucleo-mitochondrial protein belonging to the UPF0160 (MYG1) family. MYG1 is encoded by a gene that maps to human chromosome 12q13.13 and is ubiquitously expressed in simple as well as complex eukaryotes, with highest levels in testis. Considered to have a metal-dependent protein hydrolase (UPF0160) domain, MYG1 exhibits a mitochondrial targeting signal in the N-terminal region and a Pat7-type nuclear localization signal in the region between amino acids 33-39. Although MYG1 displays differential patterns and levels of expression during embryonic development, expression in normal adult tissues is stable, suggesting MYG1 involvement in early developmental processes and in adult stress/illness conditions. Elevation of MYG1 expression may be also associated with vitiligo susceptibility.
Immunogen:    Fusion protein of human C12orf10
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 25-100;WB: 200-1000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 218383(C12orf10 Antibody) at a dilution of 1/35(Nucleus and Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 218383(Anti-C12orf10 Antibody) at dilution 1/35.

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 218383(Anti-C12orf10 Antibody) at a dilution of 1/35.

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with fusion protein and then with D224304(Anti-C12orf10 Antibody) at dilution 1/35.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-3: PC-3, MCF-7 and 293T cell lysates;
Primary antibody: 218383(C12orf10 Antibody) at dilution 1/350;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 5 seconds
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