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SPRTN Rabbit pAb

Anti-SPRTN Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218403

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218403
Product Name:   Anti-SPRTN Rabbit Polyclonal Antibody
Synonyms:   DVC1; PRO4323; spartan; C1orf124
UNIPROT ID:   Q9H040 (Gene Accession – BC015740 )
Background:    The protein encoded by this gene may play a role in DNA repair during replication of damaged DNA. This protein recruits valosin containing protein (p97) to stalled DNA replication forks where it may prevent excessive translesional DNA synthesis and limit the number of DNA-damage induced mutations. It may also be involved in replication-related G2/M-checkpoint regulation. Deficiency of a similar protein in mouse causes chromosomal instability and progeroid phenotypes. Mutations in this gene have been associated with Ruijs-Aalfs syndrome (RJALS). Alternatively spliced transcript variants have been identified.
Immunogen:    Fusion protein of human SPRTN
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human ovarian cancer tissue using 218403(SPRTN Antibody) at a dilution of 1/35(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with the fusion protein and then with 218403(Anti-SPRTN Antibody) at dilution 1/35.

The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 218403(Anti-SPRTN Antibody) at a dilution of 1/35.

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with fusion protein and then with D224336(Anti-SPRTN Antibody) at dilution 1/35.
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