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CASR Rabbit pAb

Anti-CASR Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218424

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218424
Product Name:   Anti-CASR Rabbit Polyclonal Antibody
Synonyms:   CAR; FHH; FIH; HHC; EIG8; HHC1; NSHPT; PCAR1; hCasR; GPRC2A; HYPOC1
UNIPROT ID:   P41180 (Gene Accession – BC112236 )
Background:    The protein encoded by this gene is a plasma membrane G protein-coupled receptor that senses small changes in circulating calcium concentration. The encoded protein couples this information to intracellular signaling pathways that modify parathyroid hormone secretion or renal cation handling, and thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene are a cause of familial hypocalciuric hypercalcemia, neonatal severe hyperparathyroidism, and autosomal dominant hypocalcemia. [provided by RefSeq, Aug 2017]
Immunogen:    Fusion protein of human CASR
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Signal Transduction, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 218424(CASR Antibody) at a dilution of 1/100(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the fusion protein and then with 218424(Anti-CASR Antibody) at dilution 1/100.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 218424(Anti-CASR Antibody) at a dilution of 1/100.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with fusion protein and then with D224388(Anti-CASR Antibody) at dilution 1/100.
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