Email: info@neweastbio.com   |  Call: 6109452007

DACT2 Rabbit pAb

Anti-DACT2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218574

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218574
Product Name:   Anti-DACT2 Rabbit Polyclonal Antibody
Synonyms:   DPR2; DAPPER2; C6orf116; bA503C24.7
UNIPROT ID:   Q5SW24 (Gene Accession – BC111790 )
Background:    Involved in regulation of intracellular signaling pathways during development. Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors, such as TGFBR1. May be involved in control of the morphogenetic behavior of kidney ureteric bud cells by keeping cells epithelial and restraining their mesenchymal character. May play an inhibitory role in the re-epithelialization of skin wounds by attenuating TGF-beta signaling (By similarity).
Immunogen:    Fusion protein of human DACT2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Neuroscience, Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human ovarian cancer tissue using 218574(DACT2 Antibody) at a dilution of 1/30(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with the fusion protein and then with 218574(Anti-DACT2 Antibody) at dilution 1/30.
          Publications