Email: info@neweastbio.com   |  Call: 6109452007

ATP6V0D1 Rabbit pAb

Anti-ATP6V0D1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218654

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218654
Product Name:   Anti-ATP6V0D1 Rabbit Polyclonal Antibody
Synonyms:   P39; VATX; VMA6; ATP6D; ATP6DV; VPATPD
UNIPROT ID:   P61421 (Gene Accession – BC008861 )
Background:    This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c’, c’, and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is known as the D subunit and is found ubiquitously.
Immunogen:    Fusion protein of human ATP6V0D1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 218654(ATP6V0D1 Antibody) at a dilution of 1/20(Cell membrane and Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 218654(Anti-ATP6V0D1 Antibody) at dilution 1/20.
          Publications