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ZGPAT Rabbit pAb

Anti-ZGPAT Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218744

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218744
Product Name:   Anti-ZGPAT Rabbit Polyclonal Antibody
Synonyms:   ZIP; ZC3H9; GPATC6; GPATCH6; ZC3HDC9; KIAA1847
UNIPROT ID:   Q8N5A5 (Gene Accession – BC019338 )
Background:    Transcription repressor that specifically binds the 5′-GGAG[GA]A[GA]A-3′ consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis.
Immunogen:    Fusion protein of human ZGPAT
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-300;WB: 200-1000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human ovarian cancer tissue using 218744(ZGPAT Antibody) at a dilution of 1/55(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with the fusion protein and then with 218744(Anti-ZGPAT Antibody) at dilution 1/55.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 218744(Anti-ZGPAT Antibody) at a dilution of 1/55.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with fusion protein and then with D225092(Anti-ZGPAT Antibody) at dilution 1/55.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-4: Human fetal liver tissue, LO2 cell, PC-3 cell, HEPG2 cell lysates;
Primary antibody: 218744(ZGPAT Antibody) at dilution 1/400;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 2 minutes
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