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PLGLB2 Rabbit pAb

Anti-PLGLB2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218790

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218790
Product Name:   Anti-PLGLB2 Rabbit Polyclonal Antibody
Synonyms:   PLGP1
UNIPROT ID:   Q02325 (Gene Accession – BC005379 )
Background:    Cleavage of the serine proteinase plasminogen to form plasmin is the central event in the dissolution of blood clots by the fibrinolytic system. Within the fibrinolytic cascade, the serine proteinases urokinase-type plasminogen activator (uPA) and tissue-type plasminogen activator (tPA) activate the proenzyme plasminogen by cleaving plasminogen to form the fibrinolytically active enzyme plasmin. PLGLB2 (plasminogen-like B2), also known as PLGP1, is a 96 amino acid protein that resembles the N-terminal plasminogen activation peptide, which is released from plasminogen during conversion to plasmin. PLGLB2 may bind to lysine binding sites present in the kringle structures of plasminogen, an event that interfers with the binding of fibrin or à-2 antiplasmin to plasminogen and may result in the localization of activity at sites necessary for extracellular matrix destruction.
Immunogen:    Fusion protein of human PLGLB2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-300; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human liver cancer tissue using 218790(PLGLB2 Antibody) at a dilution of 1/65(Secreted).

Immunohistochemistry analysis of paraffin-embedded Human thyroid cancer tissue using 218790(Anti-PLGLB2 Antibody) at a dilution of 1/65.
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