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RAB29 Rabbit pAb

Anti-RAB29 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218833

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218833
Product Name:   Anti-RAB29 Rabbit Polyclonal Antibody
Synonyms:   RAB7L; RAB7L1
UNIPROT ID:   O14966 (Gene Accession – BC002585 )
Background:    The small GTPases Rab are key regulators in vesicle trafficking (PubMed:24788816). Essential for maintaining the integrity of the endosome-trans-Golgi network structure (By similarity). Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner (PubMed:24788816). Recruits LRRK2 to the Golgi complex and stimulates LRRK2 kinase activity (PubMed:29212815). Regulates neuronal process morphology in the intact central nervous system (CNS) (By similarity). May play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S.Typhi) epithelial cell infection (PubMed:22042847).
Immunogen:    Fusion protein of human RAB29
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 150-300; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human gastric cancer tissue using 218833(RAB29 Antibody) at a dilution of 1/120(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with the fusion protein and then with 218833(Anti-RAB29 Antibody) at dilution 1/120.

The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using 218833(Anti-RAB29 Antibody) at a dilution of 1/120.

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with fusion protein and then with D225310(Anti-RAB29 Antibody) at dilution 1/120.
          Publications