NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: S218910 | ||||
Product Name: Anti-TTC12 Rabbit Polyclonal Antibody | ||||
Synonyms: TPARM | ||||
UNIPROT ID: Q9H892 (Gene Accession – BC032355 ) | ||||
Background: TTC12 (tetratricopeptide repeat domain 12), also known as TPARM, is a 705 amino acid cytoplasmic protein containing a TPR repeat domain and three armadillo repeat motifs. TTC12 is expressed in testis, prostate, lung, germinal center B cells, neuroblastoma, teratocarcinoma, colon cancer and gastric cancer. The gene encoding TTC12 is located in a region of human chromosome 11 that is commonly deleted in a variety of cancers, therefore, it is considered a candidate tumor suppressor gene. Human chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. | ||||
Immunogen: Fusion protein of human TTC12 | ||||
Applications: ELISA, WB, IHC | ||||
Recommended Dilutions: IHC: 50-300;WB: 200-1000;ELISA: 5000-10000 | ||||
Host Species: Rabbit | ||||
Clonality: Rabbit Polyclonal | ||||
Isotype: Immunogen-specific rabbit IgG | ||||
Purification: Antigen affinity purification | ||||
Species Reactivity: Human | ||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||||
Research Areas: Cell Biology | ||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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