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IFITM2 Rabbit pAb

Anti-IFITM2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218956

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218956
Product Name:   Anti-IFITM2 Rabbit Polyclonal Antibody
Synonyms:   1-8D; DSPA2c
UNIPROT ID:   Q01629 (Gene Accession – BC009696 )
Background:    IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner.
Immunogen:    Fusion protein of human IFITM2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 30-150; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer, Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 218956(IFITM2 Antibody) at a dilution of 1/25(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the fusion protein and then with 218956(Anti-IFITM2 Antibody) at dilution 1/25.

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 218956(Anti-IFITM2 Antibody) at a dilution of 1/25.

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with fusion protein and then with D225567(Anti-IFITM2 Antibody) at dilution 1/25.
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