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GSKIP Rabbit pAb

Anti-GSKIP Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218961

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218961
Product Name:   Anti-GSKIP Rabbit Polyclonal Antibody
Synonyms:   HSPC210; C14orf129
UNIPROT ID:   Q9P0R6 (Gene Accession – BC004818 )
Background:    This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene.
Immunogen:    Fusion protein of human GSKIP
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 40-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 218961(GSKIP Antibody) at a dilution of 1/55(Cytoplasm or Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the fusion protein and then with 218961(Anti-GSKIP Antibody) at dilution 1/55.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 218961(Anti-GSKIP Antibody) at a dilution of 1/55.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with fusion protein and then with D225572(Anti-GSKIP Antibody) at dilution 1/55.
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