Email: info@neweastbio.com   |  Call: 6109452007

RPS19 Rabbit pAb

Anti-RPS19 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218964

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218964
Product Name:   Anti-RPS19 Rabbit Polyclonal Antibody
Synonyms:   DBA; S19; DBA1; eS19; LOH19CR1
UNIPROT ID:   P39019 (Gene Accession – BC000023 )
Background:    Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Immunogen:    Fusion protein of human RPS19
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 100-300; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 218964(RPS19 Antibody) at a dilution of 1/120(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 218964(Anti-RPS19 Antibody) at dilution 1/120.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 218964(Anti-RPS19 Antibody) at a dilution of 1/120.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with fusion protein and then with D225578(Anti-RPS19 Antibody) at dilution 1/120.
          Publications