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FUNDC2 Rabbit pAb

Anti-FUNDC2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219000

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219000
Product Name:   Anti-FUNDC2 Rabbit Polyclonal Antibody
Synonyms:   DC44; HCC3; HCBP6; PD03104
UNIPROT ID:   Q9BWH2 (Gene Accession – BC000255 )
Background:    FUNDC2 (FUN14 domain-containing protein 2), also known as HCC-3 (cervical cancer proto-oncogene 3 protein), HCBP6 (hepatitis C virus core-binding protein 6) or DC44, is a 189 amino acid protein belonging to the FUN14 family. The gene encoding FUNDC2 maps to human chromosome Xq28. The X and Y chromosomes are the human sex chromosomes. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. The combination of an X and Y chromosome lead to normal male development while two copies of X lead to normal female development. More than one copy of the X chromosome with a Y chromosome causes Klinefelter’s syndrome. A single copy of X alone leads to Turner’s syndrome. More than 2 copies of the X chromosome, in the absence of a Y chromosome, is known as Triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome.
Immunogen:    Fusion protein of human FUNDC2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-300; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 219000(FUNDC2 Antibody) at a dilution of 1/50(Cytoplasm or Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the fusion protein and then with 219000(Anti-FUNDC2 Antibody) at dilution 1/50.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 219000(Anti-FUNDC2 Antibody) at a dilution of 1/50.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with fusion protein and then with D225629(Anti-FUNDC2 Antibody) at dilution 1/50.
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