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PPM1B Rabbit pAb

Anti-PPM1B Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219002

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219002
Product Name:   Anti-PPM1B Rabbit Polyclonal Antibody
Synonyms:   PP2CB; PP2CBETA; PP2C-beta; PPC2BETAX; PP2C-beta-X
UNIPROT ID:   O75688 (Gene Accession – BC012002 )
Background:    The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences.
Immunogen:    Fusion protein of human PPM1B
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-300; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 219002(PPM1B Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the fusion protein and then with 219002(Anti-PPM1B Antibody) at dilution 1/50.
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