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PDE6D Rabbit pAb

Anti-PDE6D Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219212

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219212
Product Name:   Anti-PDE6D Rabbit Polyclonal Antibody
Synonyms:   PDED; JBTS22
UNIPROT ID:   O43924 (Gene Accession – BC007831 )
Background:    This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE), a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE comple,x the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants.
Immunogen:    Fusion protein of human PDE6D
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 219212(PDE6D Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 219212(Anti-PDE6D Antibody) at dilution 1/50.
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