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STK32A Rabbit pAb

Anti-STK32A Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219220

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219220
Product Name:   Anti-STK32A Rabbit Polyclonal Antibody
Synonyms:   YANK1
UNIPROT ID:   Q8WU08 (Gene Accession – BC021666 )
Background:    The phosphorylation of proteins by protein kinases and protein phosphatases is a key event in most nuclear and cytoplasmic processes. The ability to activate and deactivate proteins via phosphorylation or dephosphorylation is important for cell division, cell differentiation, DNA repair and transcription. STK32A (serine/threonine kinase 32A), also known as YANK1, is a 396 amino acid protein that belongs to the superfamily of serine/threonine protein kinases and exists as three isoforms. The gene encoding STK32A maps to human chromosome 5, which is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
Immunogen:    Fusion protein of human STK32A
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 100-200;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 219220(STK32A Antibody) at a dilution of 1/95(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 219220(Anti-STK32A Antibody) at dilution 1/95.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: Mouse heart tissue lysate;
Primary antibody: 219220(STK32A Antibody) at dilution 1/1000;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 10 seconds
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