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GCSH Rabbit pAb

Anti-GCSH Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219225

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219225
Product Name:   Anti-GCSH Rabbit Polyclonal Antibody
Synonyms:   GCE; NKH
UNIPROT ID:   P23434 (Gene Accession – BC000790 )
Background:    Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.
Immunogen:    Fusion protein of human GCSH
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 219225(GCSH Antibody) at a dilution of 1/60(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 219225(Anti-GCSH Antibody) at dilution 1/60.

The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 219225(Anti-GCSH Antibody) at a dilution of 1/60.

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with fusion protein and then with D226087(Anti-GCSH Antibody) at dilution 1/60.
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