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THG1L Rabbit pAb

Anti-THG1L Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219306

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219306
Product Name:   Anti-THG1L Rabbit Polyclonal Antibody
Synonyms:   ICF45; IHG-1; hTHG1
UNIPROT ID:   Q9NWX6 (Gene Accession – BC001523 )
Background:    The protein encoded by this gene is a mitochondrial protein that is induced by high levels of glucose and is associated with diabetic nephropathy. The encoded protein appears to increase mitochondrial biogenesis, which could lead to renal fibrosis. Another function of this protein is that of a guanyltransferase, adding GMP to the 5′ end of tRNA(His). Several transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Fusion protein of human THG1L
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 1000-5000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 219306(THG1L Antibody) at a dilution of 1/70(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 219306(Anti-THG1L Antibody) at dilution 1/70.

The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 219306(Anti-THG1L Antibody) at a dilution of 1/70.

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with fusion protein and then with D226260(Anti-THG1L Antibody) at dilution 1/70.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: HepG2 and RAMOS cell lysates;
Primary antibody: 219306(THG1L Antibody) at dilution 1/800;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 1 minute
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