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GRIK2 Rabbit pAb

Anti-GRIK2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219348

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219348
Product Name:   Anti-GRIK2 Rabbit Polyclonal Antibody
Synonyms:   EAA4; GLR6; MRT6; GLUK6; GLUR6; GluK2
UNIPROT ID:   Q13002 (Gene Accession – BC037954 )
Background:    Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive cognitive disability.
Immunogen:    Fusion protein of human GRIK2
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 219348(GRIK2 Antibody) at a dilution of 1/100(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 219348(Anti-GRIK2 Antibody) at dilution 1/100.

Gel: 6%SDS-PAGE, Lysate: 40 μg;
Lane 1-3: LOVO, Jurkat and 293T cell lysates;
Primary antibody: 219348(GRIK2 Antibody) at dilution 1/700;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 1 minute
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