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ATXN10 Rabbit pAb

Anti-ATXN10 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219480

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219480
Product Name:   Anti-ATXN10 Rabbit Polyclonal Antibody
Synonyms:   E46L; SCA10; HUMEEP
UNIPROT ID:   Q9UBB4 (Gene Accession – BC007508 )
Background:    This gene encodes a protein that may function in neuron survival, neuron differentiation, and neuritogenesis. These roles may be carried out via activation of the mitogen-activated protein kinase cascade. Expansion of an ATTCT repeat from 9-32 copies to 800-4500 copies in an intronic region of this locus has been associated with spinocerebellar ataxia, type 10. Alternatively spliced transcript variants have been described.
Immunogen:    Fusion protein of human ATXN10
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 100-300;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 219480(ATXN10 Antibody) at a dilution of 1/110(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 219480(Anti-ATXN10 Antibody) at dilution 1/110.

The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using 219480(Anti-ATXN10 Antibody) at a dilution of 1/110.

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with fusion protein and then with D227310(Anti-ATXN10 Antibody) at dilution 1/110.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: Raji and Hela cell lysates;
Primary antibody: 219480(ATXN10 Antibody) at dilution 1/800;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 3 minutes
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