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KPNA6 Rabbit pAb

Anti-KPNA6 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219497

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219497
Product Name:   Anti-KPNA6 Rabbit Polyclonal Antibody
Synonyms:   IPOA7
UNIPROT ID:   O60684 (Gene Accession – BC020520 )
Background:    Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family.
Immunogen:    Fusion protein of human KPNA6
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human gastric cancer tissue using 219497(KPNA6 Antibody) at a dilution of 1/110(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with the fusion protein and then with 219497(Anti-KPNA6 Antibody) at dilution 1/110.

The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using 219497(Anti-KPNA6 Antibody) at a dilution of 1/110.

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with fusion protein and then with D227386(Anti-KPNA6 Antibody) at dilution 1/110.
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