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TDRD3 Rabbit pAb

Anti-TDRD3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219512

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219512
Product Name:   Anti-TDRD3 Rabbit Polyclonal Antibody
Synonyms:   
UNIPROT ID:   Q9H7E2 (Gene Accession – BC030514 )
Background:    Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins.
Immunogen:    Fusion protein of human TDRD3
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 200-300;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 219512(TDRD3 Antibody) at a dilution of 1/150(Nucleus and Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the fusion protein and then with 219512(Anti-TDRD3 Antibody) at dilution 1/150.

The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 219512(Anti-TDRD3 Antibody) at a dilution of 1/150.

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with fusion protein and then with D227443(Anti-TDRD3 Antibody) at dilution 1/150.

Gel: 6%SDS-PAGE, Lysate: 40 μg;
Lane 1-3: HUVEC, NIH/3T3, MCF-7 cell lysates;
Primary antibody: 219512(TDRD3 Antibody) at dilution 1/700;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 30 seconds
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