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CDC16 Rabbit pAb

Anti-CDC16 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219588

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219588
Product Name:   Anti-CDC16 Rabbit Polyclonal Antibody
Synonyms:   APC6; CUT9; ANAPC6; CDC16Hs
UNIPROT ID:   Q13042 (Gene Accession – BC010875 )
Background:    The protein encoded by this gene functions as a protein ubiquitin ligase and is a component of the multiprotein APC complex. The APC complex is a cyclin degradation system that governs exit from mitosis by targeting cell cycle proteins for degredation by the 26S proteasome. Each component protein of the APC complex is highly conserved among eukaryotic organisms. This protein, and other APC complex proteins, contain a tetratricopeptide repeat (TPR) domain; a protein domain that is often involved in protein-protein interactions and the assembly of multiprotein complexes. Multiple alternatively spliced transcript variants, encoding distinct proteins, have been identified.
Immunogen:    Fusion protein of human CDC16
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer, Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 219588(CDC16 Antibody) at a dilution of 1/70(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the fusion protein and then with 219588(Anti-CDC16 Antibody) at dilution 1/70.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 219588(Anti-CDC16 Antibody) at a dilution of 1/70.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with fusion protein and then with D227865(Anti-CDC16 Antibody) at dilution 1/70.
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