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STING1 Rabbit pAb

Anti-STING1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219597

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219597
Product Name:   Anti-STING1 Rabbit Polyclonal Antibody
Synonyms:   ERIS; MITA; MPYS; SAVI; NET23; STING; hMITA; hSTING; TMEM173; STING-beta
UNIPROT ID:   Q86WV6 (Gene Accession – BC047779 )
Background:    This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
Immunogen:    Fusion protein of human STING1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 100-300; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Immunology, Signal Transduction, Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 219597(STING1 Antibody) at a dilution of 1/100(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 219597(Anti-STING1 Antibody) at dilution 1/100.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 219597(Anti-STING1 Antibody) at a dilution of 1/100.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with fusion protein and then with D227880(Anti-STING1 Antibody) at dilution 1/100.
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