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LOX Rabbit pAb

Anti-LOX Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219644

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219644
Product Name:   Anti-LOX Rabbit Polyclonal Antibody
Synonyms:   
UNIPROT ID:   P28300 (Gene Accession – NP_002308 )
Background:    The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Synthetic peptide of human LOX
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 25-100;WB: 500-2000;ELISA: 2000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 219644(LOX Antibody) at a dilution of 1/30(Cytoplasm, ExtraCellular space).

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the synthetic peptide and then with 219644(Anti-LOX Antibody) at dilution 1/30.

Gel: 10%SDS-PAGE, Lysate: 60 μg;
Lane: Human leiomyosarcoma tissue;
Primary antibody: 219644(LOX Antibody) at dilution 1/400;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 20 seconds
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